About the AACR Pediatric Cancer Progress Report

The inaugural AACR Pediatric Cancer Progress Report 2025 highlights how research is transforming outcomes for children and adolescents, from molecularly targeted therapies and immunotherapies to genomic profiling that informs surveillance and treatment decisions. It also includes the personal experiences of pediatric cancer survivors who have benefited from these advances.

This first-of-its-kind report also underscores the gaps in our knowledge of pediatric cancers that are rare compared to most adult cancers, and are often understudied, and emphasizes the urgent need for increased federal investments, international collaborations, and innovative approaches to address these challenges.

The report stands as both a celebration of scientific progress and an urgent call to action. With bold vision, unwavering dedication, and sustained support, together we can turn today’s challenges into tomorrow’s cures and bring new hope to children and adolescents affected by cancer.